Background Previous natural history studies highlighted a consistent heterogeneity of disability trajectories among ...

We analysed clinical trials of pharmacological interventions on patients with amyotrophic lateral sclerosis (ALS), and compared study quality and design features. The systematic review included ...

Department of Clinical Neurosciences, University of Cambridge Clinical School, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK N Robertson, Helen Durham Neuro-inflammatory Centre, Department of ...

Background: Efficient neuropsychological tests are needed to measure cognitive impairment in moderate to severe dementia. Objective: To examine construct validity of the Severe Impairment Battery ...

Department of Neuropathology, National Hospitals for Nervous Diseases, London, UK. The Lewy body is a distinctive neuronal inclusion that is always found in the substantia nigra and other specific ...

Correspondence to: Ryuji Sakakibara Department of Neurology Chiba University, 1-8-1 Inohana Chuo-ku, Chiba 260-8670 Japan; sakakibarafaculty.chiba-u.jp If you wish to reuse any or all of this article ...

Dr R Barber, Institute for the Health of the Elderly, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, NE4 6BE, U.K. Tel +(0)191 256 3274 ext. 22986; fax +(0)191 219 5048; email ...

Background: Epidemiological research on the incidence of traumatic head injuries relies on the correct definition and classification of the injury. Objective: To address the use of diagnostic criteria ...

Correspondence to Professor Yoon-Ho Hong, Neurology, Neuroscience Research Institute, Medical Research Council, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae ...

Department of Neurology, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester LE1 5WW, UK Correspondence to: Dr Y A Rajabally Department of Neurology, University Hospitals of ...

Background Many common neurological disorders are associated with advancing chronological age, but their association with biological age (BA) remains poorly understood. Methods We studied 325 870 ...