Quarterback Brock Purdy has been ruled out for his third straight game for the San Francisco 49ers due to a toe injury.

The San Francisco 49ers' injury issues continue, and they will be without yet another receive in a big Week 7 matchup.

Kyle Shanahan, as Underdog NFL shares, revealed that tight end George Kittle, who's been out since Week 1 of the season with a hamstring injury, is expected to be activated for Week 7 and have no limitations in his first game back.

The Atlanta Falcons were unsure who they would face in Sunday night's matchup with the San Francisco 49ers, but that question has been answered.

The San Francisco 49ers had quarterback Brock Purdy and tight end George Kittle back at practice on Wednesday, but are they both on track to play?

NFL Media Insider Tom Pelissero updates the injury status of San Francisco 49ers quarterback Brock Purdy and tight end George Kittle heading into their Week 7 matchup vs . the Atlanta Falcons.

The San Francisco 49ers are fighting to stay relevant in a season that keeps testing their depth. Injuries have ravaged the roster, particularly on defense, where the losses of star edge rusher Nick Bosa and linebacker Fred Warner for the year have left gaping holes in what was supposed to be an elite unit.

The Jacksonville Jaguars will face the San Francisco 49ers in Week 4 of the 2025 NFL season. Kickoff is scheduled for 4:05 p.m. ET on Sunday, September 28, 2025, at Levi's Stadium. The game will be broadcast on FOX and can be streamed on NFL+. Entering the ...

The San Francisco 49ers are off to a hot start this 2025 NFL season, going 4-1 through five weeks of pro football. However, it has also been a brutal run for them injury-wise, with several players missing games.

The Las Vegas Raiders released their final injury report of Week 7. They will head to Kansas City to face their AFC West rival.