Palladium-mediated reaction enables precision engineering of peptides and proteins
Pharmaceutical scientists at the National University of Singapore (NUS) have developed a novel chemical reaction that enables ...
Medscape21d
Advantages of mRNA Display Selections Over Other Selection Techniques for Investigation of Protein–Protein Interactions
mRNA display is similar to ribosomal display except the linkage between the mRNA and the protein is a highly stable covalent amide bond instead of noncovalent coupling through an unstable ternary ...
Technology Networks12d
Novel Reaction Enables the Precise Functionalization of Peptide Therapeutics
Researchers have applied a novel reaction to peptides produced using cell-free translation systems, providing a fast and ...
The Scientist1y
On display
In the Early Edition of Proceedings of the National Academy of Science, Wilson et al. describe how a method based on mRNA display can be used to identify ligands with higher affinity than those ...
Medscape1mon
Advantages of mRNA Display Selections Over Other Selection Techniques for Investigation of Protein–Protein Interactions
Recently, the patent rights to mRNA display technology were acquired by Bristol-Myers Squibb as a major protein design engine for the systematic development of biopharmaceuticals with high potency ...