Pharmaceutical scientists at the National University of Singapore (NUS) have developed a novel chemical reaction that enables ...
mRNA display is similar to ribosomal display except the linkage between the mRNA and the protein is a highly stable covalent amide bond instead of noncovalent coupling through an unstable ternary ...
Researchers have applied a novel reaction to peptides produced using cell-free translation systems, providing a fast and ...
In the Early Edition of Proceedings of the National Academy of Science, Wilson et al. describe how a method based on mRNA display can be used to identify ligands with higher affinity than those ...
Recently, the patent rights to mRNA display technology were acquired by Bristol-Myers Squibb as a major protein design engine for the systematic development of biopharmaceuticals with high potency ...