Crump and his colleagues inserted human outer ear enhancers into zebrafish genomes. The experiment triggered activity in the gills of zebrafish, hinting at an ancestral link between the genes in human ...
First, they put the six human outer ear enhancers that control genes into the genome of zebrafish, and they used a fluorescent reporter gene that lit up to identify the location in the body where ...
The scientists were able to incorporate enhancers that help form the elastic cartilage of the human outer ear into the genomes of zebrafish . Remarkably, the human outer ear enhancers were active ...
In the zebrafish inner ear, a cell type known as supporting cells (magenta) gives rise to new sensory hearing cells (blue). The study reveals a set of DNA control elements critical for supporting ...
This story appears in the September 2017 issue of National Geographic magazine. For a creature that’s less than one and a half inches long, the zebrafish (Danio rerio) looms large in biomedical ...
Adgrg6 is a human disease gene, and the zebrafish protein has roles both in the inner ear and in peripheral myelination. We are using the zebrafish embryo as a screening platform to identify small ...