Oral submucous fibrosis (OSF) is a serious disease that impairs mouth functionality, often leading to restricted opening and ...

We first address the etiopathophysiology of OA and the mechanisms responsible for breakdown of the cartilage extracellular matrix. We then discuss the potential of MSCs for articular cartilage ...

An interdisciplinary research team led by Professor Dr. Bent Brachvogel has examined how mitochondria influence the premature ...

“MMP-13 inhibitors might be useful in halting cartilage erosion in ... the collagen network (caused by matrix metalloproteinases [MMPs]) and extracellular matrix proteins.

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions ... Dissociated and reconstituted cartilage microparticles in densified collagen ...

This allows the cells to mature and secrete extracellular matrix components crucial for cartilage function and be implanted as soon as six to eight weeks, and integrate more quickly after ...

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.