Gene therapy has provided treatment options for diseases that are beyond the reach of traditional approaches. Since 2016, between the European Medicines Agency (EMA) and the U.S. Food and Drug ...
Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated gene insertion. These vectors typically carry at least one antibiotic-resistant ...
The presence of the central DNA flap in HIV vectors enhances gene transduction in primary neural cells. To determine whether TRIP vectors, which include the central DNA flap, allow improved ...
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