The risk of cancer goes up with age, in part because aging impedes the body's ability to detect and destroy cells with ...

Erroneous or uncontrolled cell division can have serious consequences, leading to diseases such as cancer. Plk1 plays a key role in this regulatory process. It activates other proteins involved in ...

leading to uncontrolled cell division. In addition, oncogenes can also rescue cells from programmed cell death. How does a proto-oncogene become converted to an oncogene? (Figure 4) Occasionally ...

Cancer cells are cells gone wrong — in other words, they no longer respond to many of the signals that control cellular growth and death. Cancer cells originate within tissues and, as they grow ...

The cell is then divided between the spatially separated sets of chromosomes. Erroneous or uncontrolled cell division can have serious consequences, leading to diseases such as cancer. Plk1 plays a ...

Why do these BRCA mutations increase cancer risk? All cancers are characterized by uncontrolled cell division. These rampantly growing cells usually clump into tumors, though some cells can break ...

resulting in uncontrolled cell division and, in some circumstances, cancer development. BRCA2 predisposes carriers to cancer and research has shown that BRCA2-deficient tumors respond to therapies ...