Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

spironolactone, triamterene). The primary risk of eplerenone is hyperkalemia (which can cause serious arrhythmias). Periodic monitoring of potassium levels is recommended for patients at risk of ...

In a new study, de Souza and colleagues demonstrate the potent blood pressure lowering effect of low-dose spironolactone ... such as eplerenone, and studies on these selective agents should ...

Spironolactone is contraindicated in patients with hyperkalemia, Addison's disease, or concomitant use of eplerenone (Inspra) ...