Furthermore, spike glycoprotein of SARS-CoV-2 was efficiently activated by TMPRSS13, alongside previously identified host cell protease TMPRSS2, which broadens the known cell tropism of SARS-CoV-2.

Structure of Pangolin-CoV spike protein. A EM density representation from the 2.9 Å map of Pangolin-CoV S viewed from down the three-fold axis (top panel) and in the orthogonal view (lower panel).

Scientists have discovered a mutation in SARS-CoV-2, the virus that causes COVID-19, that plays a key role in its ability to infect the central nervous system. The findings may help scientists ...

Many efforts to develop vaccines and therapies to thwart SARS-CoV-2 focus on the coronavirus spike protein, which binds the angiotensin-converting enzyme 2 (ACE2) on human cells to allow viral entry.

Swank et al. discuss a potential biomarker for identifying Long Covid in their preprint, Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae. The researchers ...

The spike protein of SARS-CoV-2, the virus that causes COVID-19, has been the focus of a lot of research these past two years. It’s what the virus uses to invade host cells and it has been the ...

On May 3, 2024, a new research paper was published in Oncotarget, entitled, “Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death ...

Investigation of Variants In SARS-CoV-2 Infections after Three Doses of COVID-19 Vaccine3 DOZ COVID-19 AŞI SONRASI OLUŞAN SARS-COV-2 ENFEKSİYONLARINDA VARYANTLARIN ARAŞTIRILMASI, Journal of ...

New research has uncovered a series of mutations in the SARS-CoV-2 spike protein that enhanced the virus' ability to infect the brains of mice. The findings may help scientists understand its ...

Scientists have discovered a mutation in SARS-CoV-2, the virus that causes COVID-19, that plays a key role in its ability to infect the central nervous system. The findings may help scientists ...