A personalized tumor ... DNA samples were sequenced to identify tumor-specific mutations in 155 cancer-associated genes. Top personalized mutations with the highest ranking scores were used to detect ...

Use of a standardized cell-free (cf)DNA-sequencing and cancer-screening ... Of the 20 participants with solid tumors, two had stage I disease, five had stage II or III disease, and 13 had stage ...

"For solid tumors—the major killers in cancer—there ... refers to chemical modifications to the genome that don't change the DNA sequence. If DNA is a cell's hardware, the epigenome is the ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

However, traditional CAR T cell therapy has had limited success in solid tumors. Shipra Das, an immunooncologist at Cellectis, discussed a novel approach using transcription activation-like effector ...

DNA sequencing can uncover the complex genetic and epigenetic factors that cause aggressive paediatric cancers and their recurrence.

SMPaeds2 will investigate blood cancers and solid tumors in children and ... Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution ...

Optimal therapeutic targeting of cancer involves clonal signals which are expressed within all cancer cellsGradalis applies a novel clinically ...

This method, called DNA sequencing, is already available through the NHS for other cancers. These results mean that tumor DNA sequencing may provide a more effective way to predict a patient's risk of ...