The hereditary motor and sensory neuropathies (also known as Charcot–Marie–Tooth disease or CMT) are characterized by a length-dependent loss of axonal integrity in the PNS, which leads to progressive ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

"Alterations in axonal membrane and channel function occur early in the disease course, prior to discernable large fibre involvement, and has the potential to be used as an early biomarker of ...

Giant axonal neuropathy (GAN) is a rare, autosomal recessive neurodegenerative disorder, characterized by a spectrum of symptoms and a challenging prognosis. Now, a study published recently in the New ...

Chronic inflammatory demyelinating polyneuropathy is an immune-mediated neuropathy that affects the peripheral motor and sensory nerves. The symptoms are of a slowly progressive numbness and tingling ...

Sensory nerve action potential amplitudes decreased as patients aged in a cohort of spinal muscular atrophy (SMA) type 1 patients compared with a healthy, age-matched control group. Spinal muscular ...

Giant axonal neuropathy is a rare, autosomal recessive, pediatric, polysymptomatic, neurodegenerative disorder caused by biallelic loss-of-function variants in GAN, the gene encoding gigaxonin. We ...

Considering taking supplements to treat Hereditary motor and sensory neuropathy? Below is a list of common natural remedies used to treat or reduce the symptoms of Hereditary motor and sensory ...

There are more than a hundred types of peripheral neuropathy, including mononeuropathies and polyneuropathies. These include damage to the axons, or to the myelin sheath, or both. Accidents, including ...

Thirty-three patients with liver cirrhosis were investigated clinically and electrophysiologically. Nerve-conduction abnormalities were present in 24 (73%) patients compared with 71% reported in a ...

Rockville, MD - The disease-modifying antirheumatic drug leflunomide (Arava, Aventis) is associated with peripheral neuropathy in some patients, say FDA researchers who reviewed 80 case reports ...