Please provide your email address to receive an email when new articles are posted on . Nearly 10% of patients with systemic sclerosis had systemic sclerosis sine scleroderma, a subtype without skin ...

SAN DIEGO — Clinicians managing systemic sclerosis should focus on treating “what is treatable” in each organ that is involved, according to data presented at the 2024 Congress of Clinical ...

AMSTERDAM — For patients with diffuse cutaneous systemic sclerosis, an autoimmune disease for which there are few treatment options, lenabasum (JBT-101, Corbus Pharmaceuticals) shows potential, new ...

Patients who underwent autologous stem cell transplantation (ASCT) for diffuse cutaneous systemic sclerosis (dcSSc), also known as scleroderma, did no better than others receiving conventional ...

Scleroderma is a chronic autoimmune disease of women. Over time, people living with scleroderma develop progressive and irreversible scarring. Scarring, called fibrosis, affects the lungs, heart and ...

Click to share on X (Opens in new window) X Click to share on Facebook (Opens in new window) Facebook Design by Evelyn Mousigian. Dr. John Varga, rheumatology, internal medicine and dermatology ...

Patients with scleroderma renal crisis demonstrated specific enrichment of CD14+ monocytes with increased EGR1 expression and activation of NF-κB–related pathways. Trajectory analysis indicated that ...

Systemic sclerosis (SSc) or scleroderma is a rare, chronic, autoimmune disorder that hardens connective tissue and muscle in the body. As a result, this can generate complications associated with skin ...

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that patients with refractory juvenile systemic sclerosis improved significantly on nearly all ...

Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology. Characterized by ...

Cyclophosphamide is widely used to treat severe manifestations of numerous autoimmune rheumatic diseases including systemic sclerosis. Based on recent data, immunological and inflammatory activation ...