JSTOR Daily

On Sample Size and Quick Simultaneous Confidence Interval Estimations for Multinomial Proportions

Asymptotically, sample proportions from a multinomial distribution converge in distribution to a multivariate normal distribution with a singular negative product correlation structure. Based on this ...
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Trevi Therapeutics Announces Positive Outcome of the Sample Size Re-Estimation Analysis in PRISM Trial for Severe Pruritus in Patients With Prurigo Nodularis

NEW HAVEN, Conn., July 13, 2020 (GLOBE NEWSWIRE) -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company focused on the development and commercialization of Haduvio ...
ascopubs.org

Bayesian Sample Size Planning Tool for Phase I Dose-Finding Trials

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...
JSTOR Daily

Diseases Having Two Classes of Severity: Estimation of the Proportions of Each Manifestation by Maximum Likelihood

In diseases having variable expressivity, the proportions of the different manifestations of the affection in the population may be different from the observed proportions in a sample when ...
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Aevi Genomic Medicine Provides Update on Sample Size Re-estimation for Phase 2 ASCEND Trial in ADHD

PHILADELPHIA, June 12, 2018 /PRNewswire/ -- Aevi Genomic Medicine, Inc. (NASDAQ: GNMX) (the Company) today announced that it will increase the sample size for Part A of its Phase 2 ASCEND clinical ...