Age-related macular degeneration begins with weakening of retinal pigment epithelium cells (RPEs), a layer of cells that support the retina's photoreceptors. When degeneration occurs, the affected ...

the irreversible degeneration of the retina—a layer of photoreceptors at the back of the eye—can cause impaired vision and lead to blindness. Although millions of people worldwide suffer from retinal ...

comparing three mouse models of inherited retinal degeneration to healthy wild-type mice. "Our data facilitate the development of new therapeutic strategies that do not rely on specific genetic ...