KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid is in Nature Microbiology.

This specificity narrows the ability to use the LacI system in cases where researchers can’t insert this sequence, prompting a search for a more flexible repressor protein that can recognize more ...

Control at the translation level After a gene has been transcribed, control mechanisms can still regulate its expression during the translation process. Within eukaryotes, special repressor ...

How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...

or after a gene's transcription start site. It is the spacing, or 'ambience,' that determines if a given transcription factor ...

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs. Bacteria have multiple defense ...