Cells have proteins called receptors that bind to signaling molecules ... and tyrosine are especially common sites for phosphorylation. These phosphorylation reactions control the activity of ...

A newly discovered bat coronavirus uses the same cell-surface protein to gain entry into human cells as the SARS-CoV-2 virus that causes COVID-19, raising the possibility that it could someday spread ...

The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with variations in receptor function. Computational protein structure prediction ...

“A key challenge is that subtle structural changes can have profound functional consequences, and thus cell therapies can benefit from improved methods for tuning receptor functions at the ...

Ferreira pointed to a recent clinical trial conducted at 15 sites across ... chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells, Molecular Therapy ...

When the SARS-CoV-2 virus enters the human body, it breaks into cells with the help of two proteins that it finds there, ACE2 and TMPRSS2. While there has been much discussion of viral infection in ...

The "Chimeric Antigen Receptor T-Cell Therapy (CAR-T) - Pipeline Insight, 2025" report has been added to ResearchAndMarkets.com's offering. The Chimeric Antigen Receptor T-Cell Therapy (CAR-T) ...

A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.