Immediate use for the newly developed assembloids could include studying neurodevelopmental disorders such as autism.

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This ...

Scientists recreate brain’s pain circuit in world first - Breakthrough could unlock mysteries of chronic pain and ...

9 Central sensitisation can be seen as an umbrella term,9 the main characteristics of which are: Hyperalgesia is an increased pain response to normally painful stimuli and may be as a result of ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

In the periphery, TRPV1 is activated by exposure to noxious heat and protons and is responsible for peripheral heat hyperalgesia. Central sensitization is a major problem in pain conditions across ...

Stanford Medicine investigators have replicated, in a lab dish, one of humans' most prominent nervous pathways for sensing ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

A groundbreaking study has uncovered new insights into the pain pathways associated with temporomandibular joint (TMJ) disorders. Using an innovative in vivo imaging tool to capture functional ...

Systemic inhibition of interleukin (IL)-1 with rilonacept (IL-1 Trap) could be an effective therapy for the pain and inflammation ... ankle joint synovitis and hyperalgesia induced by monosodium ...