A particular nuclear hormone receptor called DAF-12 and molecules called microRNAs in the let-7 family form a molecular switch that encourages cells in the larvae of a model worm to shift to a ...

A particular nuclear hormone receptor called DAF-12 and molecules called microRNAs in the let-7 family form a molecular switch that encourages cells in the larvae of a model worm to shift to a ...

An important conceptual advance in hormone biology is the finding that, in addition to conventional membrane-bound hormone receptors, the main receptors of several plant hormones are localized in ...

DiscoveRx has developed a cell-based nuclear hormone receptor (NHR) assay using its enzyme fragment complementation (EFC) technology that provides notable benefits for screening and profiling ...

Nuclear hormone receptors are transcription factors that regulate multiple biological pathways and may provide protection against metabolic, inflammatory and cardiovascular diseases. In this ...

A new Salk Institute study suggests that estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue.

(Cited in about 300 papers since publication) By interacting with their nuclear receptors, hormones regulate a wide variety of physiological functions, including metabolism, growth, and cell ...

The striking capacity for plants to adapt their growth and development to an ever-changing environment is mediated by diverse plant hormones that regulate virtually every aspect of plant life. In ...

“Nuclear receptors are the only class of DNA-binding proteins that are druggable. Drug development has been focused exclusively on designing artificial hormones that would replace the natural ones and ...

Nuclear hormone receptor signaling for cancer research studies the effect of different bind sequence specific promoter elements on cancer cells.