For this article, Nadia S. Halim interviewed Ronald Evans, professor in the gene expression laboratory, Salk Institute, La Jolla, Calif., and Hongwu Chen, postdoctoral fellow, Salk Institute. Both are ...

Nuclear receptors are popular targets for drug companies searching for new therapeutics for cancer and cardiovascular, metabolic, inflammatory, and other diseases. Indigo Biosciences in State College, ...

Researchers describe a new manner of detecting microbial infection that intercepts pathogen-derived signals of growth to assess the relative threat of virulent bacteria. A nuclear hormone receptor in ...

S.A. Kliewer, L. Umesono, D.I. Mangelsdorf, R.M. Evans, "Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone, and vitamin D ...

Chinese Medical Journals Publishing House Co., Ltd. Brain cancer is one of the most aggressive and life-threatening diseases, with glioblastoma (GBM) being the most common and deadliest type. Patients ...

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development ...

LA JOLLA (May 12, 2025)—A new Salk Institute study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue. Across the body, tiny bean-shaped structures ...

A bitter taste has always been considered a warning signal, devoted to protecting us from ingesting potentially harmful ...

What is love? Scientists want to know, too. But, it turns out, they may have been looking in the wrong places. Stanford Medicine researchers and colleagues at two other institutions report surprising ...