Q4 2024 Management View CEO Paula Ragan highlighted 2024 as a transformative year for X4 Pharmaceuticals, with the U.S. approval and launch of XOLREMDI (mavorixafor) for WHIM syndrome, a rare ...

When the neutrophil count is too low, it is known as neutropenia. Typically, a low neutrophil count (neutropenia) results in ...

Phase 3 4WARD trial in chronic neutropenia now activated at ~90% of targeted trial sites; full enrollment expected in 3Q or 4Q 2025; top-line ...

Clozapine is also associated with a rare side effect called neutropenia, a drop in white blood cell counts that, in its most severe form, can be life-threatening. In 2015, federal regulators ...

The risk for severe neutropenia (ANC count less than 500 cells/uL) still exists, and will still be listed within the boxed warning on all clozapine products. Severe neutropenia, which is ...

The FDA has eliminated the need for pharmacists to verify a patient's white blood cell count before dispensing the antipsychotic medication clozapine.

Neutropenia in individuals with a congenital defect or patients with cancer who are undergoing chemotherapy is generally treated with granulocyte colony-stimulating factor (G-CSF) to restore ...

The Clozapine REMS program was established in 2015 due to the risk of severe neutropenia associated with the medication. Prior to pharmacies dispensing clozapine, the FDA required patients to ...