The neural crest is an extraordinary population of multipotent stem cells, unique to vertebrates, that plays a pivotal role in embryogenesis. Arising at the borders of the neural plate, these cells ...

Neural crest cells have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development. But their capacity to form derivatives ...

A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of ...

Based on conserved developmental principles, we have developed a simple but highly efficient platform to convert human PSCs into neural tissue. We have shown that dual-SMAD inhibition via small ...

The image shows induced human neural crest cells. Human embryonic stem cells display neural crest characteristic expression after only five days of culture under WNT induction. Transcription factors ...

Scientists have visualised the early development of the nervous system in a chicken embryo. Minyoung Kim at the University of California, San Francisco, dissected the 2-day-old embryo out of its egg ...