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the team found that naive T cells—cells that have never encountered an antigen—and memory T cells were more likely to take up telomeres. Meanwhile, various types of effector T cells are less likely to ...
While naïve T cells lacked the disease-fighting imprinting of memory cells, they became more effective when RUNX2 was added. They also lived longer and the gene protected them against exhaustion ...
“The compartmentalization [of naive T cells] is the biggest story.” Previous studies of immune cell populations in people relied on blood samples to pick up circulating T cells, but the Columbia team ...
T & B cells in aging The pool of naive cells is reduced, while effector memory and potentially dysfunctional late-differentiated cell numbers are increased. Expansion of antigen-specific T cells ...