Microglial activity appears to determine when amyloid becomes biologically significant, reshaping how clinicians interpret ...

A new study, published today in Nature Communications, offers clues into how APOE isoforms differentially affect human microglia function in Alzheimer's disease. The study, led by Dr. Sarah Marzi and ...

Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate ...

A rare but potent genetic mutation that alters a protein in the brain’s immune cells, known as microglia, can give people as much as a three-fold greater risk of developing Alzheimer’s disease. A new ...

In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A new study uncovers how a key immune cell, called a microglia, might be the ...

Tiny charming immune cells called microglia protect the central nervous system in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate ...

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another “crew” of responders is busy clearing debris and ...

Researchers now want to understand if other environmental exposures impact microglia similarly, and whether these changes lead to long-term alterations in brain circuitry and function. Lowery, R.L., ...

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...