Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

The production of megakaryocytes (MKs) and platelets from stem cells is a rapidly evolving field with significant implications for treating conditions like thrombocytopenia, where patients have ...

murine model was due to reduced proliferation of megakaryocyte erythroid progenitors and increased apoptosis of erythroblasts. Colony-forming cell assays indicated that the leukemic bone marrow ...