A University of Tokyo research group has revealed for the first time the three-dimensional structure and mechanism of action of a key enzyme of bio-fuel production, cellobionic acid phosphorylase ...

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen that is often associated with healthcare settings but can cause serious infections in anyone. These illnesses are difficult ...

To understand what has gone wrong when cancer occurs and to create new possibilities for treatment, it is important to understand the molecular mechanisms behind what is happening at the cellular ...

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the ...

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the Institute of Science Tokyo reveal that a tandem allosteric effect of ...

Tulane researchers discovered a new pain signaling mechanism that could lead to safer, more effective treatments and reshape ...

WITH our present knowledge of enzyme processes any conception of their mechanism must be essentially highly speculative. In the work under notice the author makes no claim to deal comprehensively with ...

Ten years ago, researchers obtained the first crystal structure of Dicer, a key enzyme in a biological process called RNA interference (RNAi). In RNAi, a process also known as gene silencing, a short ...

A new study led by scientists at IUPUI and Indiana University Bloomington is the first to describe a biochemical mechanism that increases the activity of a molecule whose presence is observed in many ...

(Nanowerk News) An international research team led by the University of Leicester has made a breakthrough advance by trapping an intermediate in the mechanism of enzymes called heme peroxidases and ...

A team of researchers in China has found a reaction mechanism unprecedented for the many enzymes that add methyl groups to biomolecules. Although NosN uses two SAM molecules, neither of them serves ...