This enzyme's selectivity for RNA, its high methylation activity ... an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency, Nucleic Acids Research (2024).

(D) RNA m6A methylation level of LINC00901 as determined by EpiQuik m6A RNA Methylation Quantification Kit. In vivo expressed S1m-tagged LINC00901 or vector control (S1m) was pulled down by ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation ... Drosophila m6A ...

Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...

One of the most abundant and significant modifications in RNA is m6A, which influences RNA processing, stability, and translation into proteins. However, its role in cancer-particularly prostate ...