ToxPredictor accurately predicts drug induced liver injury (DILI) to offer a valuable “go/no-go” tool in clinical decision making.

The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...

Absorption, Distribution, Metabolism, and Excretion (ADME) are important parameters to determine the pharmacokinetic profile of a drug, and therefore a crucial measurement for drug efficacy. Animal ...

October represents a month of liver awareness, marked by many countries as a time to reflect on an incredibly resilient, yet vulnerable, organ. Liver disease is a growing problem worldwide, but ...

The global human liver model market was valued at USD 1.19 billion in 2023 and is projected to expand at a robust CAGR of 13.8% from 2024 to 2030, culminating in a market size of USD 3.19 billion by ...

Researchers at Science Tokyo have created a lab-grown liver organoid that mimics regeneration and scarring, offering a new platform to study fibrosis and test therapies that could reverse chronic ...

After the recent implementation of acuity circle (AC)-based allocation policies, overall mortality and dropout rates among severely ill liver transplant candidates decreased; however, candidates with ...

In severe cases, a viral hepatitis infection can result in liver failure. A team from the Technical University of Munich (TUM) has now discovered how this occurs: by immune cells attacking cells in ...

CINCINNATI—Researchers at Cincinnati Children’s Hospital Medical Center in collaboration with Roche, have developed a next-generation human liver organoid microarray platform that that could help ...

Sophisticated medical criteria will be used to rank patients waiting for donated livers under a system approved unanimously by the nation's transplant network. The new system replaces one that relies ...