How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...

This is a preview. Log in through your library . Abstract The nucleotide sequence of the control region of the leu operon of Salmonella typhimurium was determined. A prominent feature of this region ...

The nucleotide sequence of the region preceding the transcription initiation site of the tryptophan operon of Escherichia coli was determined. Essentially all of the trp operator precedes the ...

Support for the hypothesis that transcription is initiated before the operator region of the trp-operon of E. coli, and that the repressor, in binding to the operator region, directly blocks the ...