achieved its primary endpoint in participants with cervical high-grade squamous intraepithelial lesions (HSIL). HSIL are precancerous lesions linked to human papillomavirus (HPV) that can lead to ...
The incidence of cervical intraepithelial neoplasia (CIN ... A large majority of high-grade lesions in the female genital tract emerge as monoclonal cell populations derived from the cervical ...
Focusing development efforts for cancer-preventive drugs on precancerous lesions (that is,intraepithelial neoplasia (IEN)) can reduce costs and accelerate the emergence of new cancer-preventive drugs.
Researchers at the University of Pittsburgh have identified a novel trigger for a deadly form of ovarian cancer: a subset of ...
Lesion size was significantly reduced in all ... a therapeutic vaccine for patients with HPV16-positive high-grade cervical intraepithelial neoplasia: a Phase II trial, Clinical Cancer Research ...
The Anal Cancer/High-grade squamous intraepithelial lesions Outcomes Research (ANCHOR) trial demonstrated that treating precancerous anal HSIL reduces the incidence of anal cancer by 57% in people ...
Abstract Thinking and Statins With Immune Checkpoint Inhibitors: Enough to Change Clinical Practice? Using an index designed and validated for use in ANCHOR, HRQoL was assessed before random ...