In a healthy individual, T cells find cancer cells and release the protein interferon-gamma, a potent cytokine that stops tumor growth. However, interferon-gamma has limited effects on directly ...

The increase in IL-12 levels was accompanied by localized increases in interferon-gamma (IFN-g ... the ability of IMNN-101 to induce an immune response to the SARS-CoV-2 Omicron XBB1.5 spike ...

C57BL/6 mice deficient in interleukin12 or gamma interferon showed faster acute ... xenograft responses were skewed towards an acute vascular response, resulting in rapid rejection of transplanted ...

Gene set enrichment analysis showed enriched gene sets for interferon-gamma and -alpha response, inflammatory response, allograft rejection, fatty acid metabolism, and oxidative phosphorylation.

The Katherine King lab members are involved in the study of the role of interferon-gamma in hematopoietic stem cell regulation. Dr. King discusses the impact of receiving an AAMDSIF research grant on ...