A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome — ...

Using various wild-type and cytokine-deficient mice strains, we have examined the mechanisms of acute vascular rejection. C57BL/6 mice deficient in interleukin12 or gamma interferon showed faster ...

We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell (HSC ... and defined the transcriptional and epigenetic mechanisms underlying the Dnmt3a-loss of function clonal selection ...

In a healthy individual, T cells find cancer cells and release the protein interferon-gamma, a potent cytokine that stops tumor growth. However, interferon-gamma has limited effects on directly ...