Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of newborn mortality and morbidity worldwide, and lowering the baby's body temperature—called therapeutic hypothermia—is often used ...

Brain injuries are a leading cause of death and long-term disability in infants. Among the most common is neonatal hypoxic-ischemic encephalopathy (HIE), which affects one to three in 1,000 live ...

People who climb too fast or too high risk acute altitude sickness, which can lead to life-threatening hypoxic brain injury. By using in vivo electrochemistry, researchers demonstrated that ...

Ischemia and reperfusion can cause death and illness. The interruption of the arterial blood supply to a single organ or to multiple organs leads to hypoxic injury and cell death. In cases in which ...

The condition, known as hypoxic-ischemic encephalopathy (HIE), can result in severe brain damage, which is why researchers are studying the condition to evaluate how HIE is treated and develop new, ...

Provoked seizures are not considered to be epilepsy, which is defined as two or more unprovoked seizures, and provoked seizures typically do not require long-term treatment with antiseizure medication ...

Lowering the body temperature of preterm infants (born at 33 to 35 weeks of pregnancy) with hypoxic ischemic encephalopathy (HIE)-a type of brain damage caused by oxygen loss-offers no benefits over ...

image: Potential role for PKA-dependent HIF-1α stabilization at the interface of hypoxia and inflammation. HIF stabilization during hypoxic or ischemic tissue conditions can dampen hypoxia-driven ...