If the prior cytology report was ASC-US or LSIL, observation with annual cytology is recommended. If the prior report was ASC-H or HSIL, management depends on colposcopic findings.

HSIL identified by any biopsy was the reference standard of disease used to evaluate the incremental yield and sensitivity of multiple biopsies. Results. ... The highest increase in yield of HSIL was ...

We and others use techniques for anal screening adapted from the cervix, including anal cytology, high-resolution anoscopy (HRA)-guided biopsy of lesions, and treatment of biopsy-proven anal HSIL.

Existing algorithms to screen for anal cancer in women living with HIV could be missing many cases of anal high-grade squamous intraepithelial lesions (HSIL) – abnormal tissue changes that may be a ...

Anal cytology is graded similarily to cervical pathology. Precancerous cells (high-grade squamous intraepithelial lesion [HSIL])4 occur in 10% of HIV-positive MSM and should be referred for HRA. Lower ...

Both cervical and anal cancer are caused by human papillomavirus. Both diseases also share a common precursor: abnormal cells known as high-grade squamous intraepithelial lesions (HSIL). In ...

This study was approved by the Institutional Review Board of Hawaii Pacific Health. Patients were selected from the gynecologic cytology practice of a community commercial laboratory, which ...

The peak in HSIL or precancer occurs 5 to 10 years ... Zerat, L, et al. Evaluation of oncogenic human papillomavirus RNA and DNA tests with liquid-based cytology in primary cervical cancer ...

Cytology is used as a rapid method to triage patients with HPV whereas histology is considered the gold standard for cervical cancer diagnosis. Histological analysis, however, is more invasive and ...