Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

Thus, histone modifications generally represent a more complex and diverse mechanism to affect gene transcription than DNA methylation. In fact, one effect of DNA methylation can be to recruit ...

Histone deacetylation and other modifications, particularly the methylation of lysine 9 within histone H3 (H3-K9) residues located in the histone tails, cause chromatin condensation and block ...

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

To compact the DNA, plants use various epigenetic marks, including DNA methylation and modifications of the histone proteins ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Using animal models, he, Dempsey, and the rest of their research team found that H3K36 methylation -- a biochemical process that occurs within the H3 histone protein -- is responsible for turning ...

"The changes that happen with the fat exposure, the changes in metabolism and the changes in histone methylation and gene expression are the types of changes that can be associated with hormone ...