Researchers have discovered a molecular circuit involving the oxygen-carrying component of hemoglobin -- heme -- that helps maintain proper metabolism in the body, providing new insights into ...

Lysine-specific demethylase 1 (LSD1), an enzyme involved in gene expression, produces individualized metabolism depending on the type of acute myeloid leukemia cells. Cancer cells have a unique ...

This laboratory is engaged in the study of how intrarenal mononuclear phagocytes regulate kidney homeostasis and disease, and how they modulate a transition from acute to chronic disease. A second ...

They looked at 37,544 participants’ plasma metabolic biomarkers, including those related to insulin levels, blood sugar, blood lipids, inflammation, and two biomarkers of iron metabolism.

Higher intake of heme iron, the type found in red meat and other animal products-;as opposed to non-heme iron, found mostly in plant-based foods-;was associated with a higher risk of developing ...

A St. Jude study reveals how glutamine metabolism shifts during red blood cell maturation to prevent oxidative stress and support heme production. Disruptions in this process contribute to disorders ...