The germinal centers that form in the body's lymph nodes work as a fitness boot camp in which B cells evolve to produce antibodies of increasingly higher affinity to an invading pathogen. This new ...

Germinal centers form in the body's lymphatic tissues shortly after vaccination or infection. Once inside a germinal center, B cells undergo rapid mutations and, ...

Continuous germinal center invasion contributes to the diversity of the immune response. Cell , 2023; 186 (1): 147 DOI: 10.1016/j.cell.2022.11.032 Cite This Page : ...

The germinal centers that form in the body's lymph nodes work as a fitness boot camp in which B cells evolve to produce antibodies of increasingly higher affinity to an invading pathogen. This new ...

Multi-center project will profile over 40,000 samples using ultra-sensitive NULISA™ technology. How Alderley Analytical are Delivering eXtreme Robustness in Bioanalysis Discover how Alderley ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells ...

Germinal centers are made up of two distinct regions – the light zone and dark zone, with some cells located in specific areas, and others which move between the zones.

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells ...

Germinal centers can be visually divided into a dark zone and light zone. For the proliferation and differentiation to occur, B cells must cycle between the two zones.

The prognostically favorable germinal-center B-cell gene-expression signature is notable because cell lines derived from germinal-center B-cell–like diffuse large-B-cell lymphomas have decreased ...