Monitoring tumor markers may be an effective relapse-detection strategy for certain children with nongerminomatous malignant germ cell tumors, according to a study published in Journal of Clinical ...

Stem cell markers, OCT3/4, and more recently SOX2 and growth differentiation factor 3 (GDF3), have been reported to be expressed variably in germ cell tumors. We investigated the ...

Serum tumor markers play a critical role in the diagnosis, staging, risk stratification, and surveillance of patients with testicular germ cell tumors (GCTs).

Ovarian germ cell tumors are usually found in teen girls or young women. Less often, women who are in their 60s can get this tumor.

Ovarian cancer tumor markers are chemical compounds that cancer cells produce. Doctors can use different types to help diagnose ovarian cancer.

Germ cell cancer can develop in children and adults. Researchers don’t know exactly what causes germ cell cancers to form, but they have identified some risk factors.

Tumor markers help doctors diagnose testicular cancer, determine treatment, and monitor how well that treatment is working. Learn more.

The markers can be used to detect relapse with a high degree of sensitivity in patients with CNS nongerminomatous germ cell tumors, according to a pooled analysis of cooperative group trials.

Comprehensive genomic profiling (CGP) in patients with relapsed/refractory germ cell tumors (GCT). P3BEP (ANZUP 1302): An international randomized phase III trial of accelerated versus standard BEP ...

A meta-analysis of nearly 200,000 men revealed 22 new genetic locations that could be susceptible to inherited testicular germ cell tumors.

In this issue of the Journal of Clinical Oncology, Fizazi et al report an analysis of predicted time to normalization of serum tumor markers during the first cycle of chemotherapy in men with ...

Non-seminoma is a type of germ-cell testicular cancer. Learn more about its symptoms, risk factors, treatment options, and outlook here.