The publication, titled “ Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency” highlights the potential of MG119-28 (formally ...

This guidance emphasises the potential of NGS methods in mitigating safety risks associated with therapies incorporating ...

The draft guidance supports the agency’s new pathway designed to speed up the development of custom gene therapies.

The genome has thousands of genes that code for proteins, which help carry out many of the cell's important functions. But ...

Gene‑edited HPSCs programmed to make therapeutic antibodies and proteins show long‑lasting, boostable immunity in mouse models.

A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

NIH-funded UT team and colleagues from Metagenomi Thereapeutics discovered highly efficient enzyme could enable targeted gene editing within the human body.

Most gene-editing tools are blind to context. Point them at a DNA sequence and they cut, whether that sequence sits inside a ...

The US Food and Drug Administration (FDA) has released draft guidance on how sponsors can utilize next-generation sequencing ...

Key market opportunities include advancements in research, medicine, diagnostics, and biotechnology through CRISPR. There is potential for innovative solutions and ethical exploration in gene editing, ...

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...

Scientists at Rothamsted Research have successfully developed wheat with dramatically reduced levels of asparagine, without ...