DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and epigenetic state. By analyzing thousands of sequences, the method showed that ...

From infancy and usually for life, some families suffer from broken hair due to a congenital form of hair loss called monilethrix. Researchers at have now identified causative mutations in another ...

Scientists have discovered how a primary genetic risk factor for Alzheimer's causes the disease as well as a potential solution to erase the damage caused by it. While there is no specific gene that ...

Less than 2% of the genome codes for proteins; the rest, once called 'junk DNA', contains regulatory elements. Researchers analyzed 10,000 to reveal how variants shape gene activity.

(from left) Dr. Buket Basmanav, Nicole Cesarato, Xing Xiong, Prof. Regina Betz and Yasmina Gossmann find causative mutations in the keratin 31 gene for the dominantly-inherited form of monilethrix.