In a recent Nature Communications article, researchers introduced destabilized near-infrared (NIR) fluorescent nanobodies designed to target green fluorescent protein (GFP)-based biosensors. These ...

Osamu Shimomura, Distinguished Scientist Emeritus at Marine Biological Laboratory, died Oct. 19 at the age of 90. He shared the 2008 Nobel Prize in Chemistry for his work on isolating green ...

Roger Tsien's group at the University of California San Diego has a knack for tinkering with fluorescent proteins. In 2004, they published a follow-up to a 2002 paper reporting the first monomeric red ...

Following chemist and marine biologist Osamu Shimomura’s success in determining the structure of luciferin from a crustacean at Nagoya University, Frank Johnson, then a biologist at Princeton ...

Modern bioassays tend to fall under three common modalities: colorimetric, luminometric or fluorometric. Colorimetric assays record the amount of light absorbed by a reporter compound. This absorbance ...

Holly has a degree in Medical Biochemistry from the University of Leicester. Her scientific interests include genomics, personalized medicine, and bioethics.View full profile Holly has a degree in ...

Due to the 4-hour maturation half-life of the Timer protein's blue-to-red chromophore, we can detect reactivated or recently silenced proviruses with high sensitivity using Timer fluorescence.