A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...
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Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
Evolution of HER2 scores after neoadjuvant systemic therapy in breast cancer. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full text component ...
Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects ...
In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for ...
A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to ...
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