As reviewed extensively elsewhere, [5] many factors have been found to determine tumor response to radiotherapy. Intrinsic determinants of radiation sensitivity include DNA repair capability, cell ...
The cancer stem cell (CSC) hypothesis is an attractive model to account for the functional heterogeneity that is commonly observed in solid tumours. It proposes a hierarchical organization of cells ...
Cancer stem cells (CSC) can be difficult to define, even for biologists. In order to understand CSCs, cancer itself must be thought of as highly organized – comprised of cancer cells that have a ...
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