Gastrulation leads to three germ layers—ectoderm, mesoderm and endoderm—that are separated by two basement membranes. In the mouse embryo, the emergent gut endoderm results from the widespread ...
Uniting three different parameters in single cells taken from mouse embryos reveals more about how foundational cell identities are established in early development The first single-cell multi-omics ...
(Philadelphia, PA) – Researchers at the Lewis Katz School of Medicine at Temple University have discovered that the Hippo signaling effector YAP1 is a master regulator of Nodal signaling in human ...
Engineers and a pediatric surgeon have joined forces to discover that physical forces like pressure and tension affect the development of limbs in embryos -- research that could someday be used to ...
Embryonic cells learn their fate early in development. Discovery of a factor that controls the development of one embryonic tissue, the ectoderm, highlights a mechanism that might also influence the ...
When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...
With the construction of a building, one of the first steps before creating the upright structure is to set the foundations and the floorplan. Mammalian development is not so different. A ...
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