Dendritic cell receptors, in particular C‐type lectins such as DC-SIGN, play a pivotal role in the immune response by recognising and internalising diverse glycan structures present on pathogens. The ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

As tumors outgrow their blood and nutrient supplies, or respond to treatments like chemotherapy and radiotherapy, individual cancer cells die, exposing their internal scaffolds.

As tumors outgrow their blood and nutrient supplies, or respond to treatments like chemotherapy and radiotherapy, individual ...

New research from the Francis Crick Institute and Adendra Therapeutics shows that immune cells can be redirected to recognise cancer by exploiting F‑actin, a structural protein exposed when tumour ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

For her Ph.D. at VUB and KULeuven, Aarushi Caro created a kind of systematics for dendritic cells, a special group of immune cells in the fight against cancer. Until now, there was a lot of confusion ...

Engineered nanoparticles can improve cancer immunotherapy by delivering drugs, antigens, and genetic payloads with greater ...

New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides through a dendritic cell-like pathway that may shape early coeliac ...

The rapid clinical validation of mRNA technology during the COVID‑19 pandemic has powerfully accelerated its application in ...

All cells, whether big or small, short or long, rely on proteins to function properly. In most cells, transporting these ...