Dendritic cells (DCs) have a variety of features that make them highly effective agents for detecting pathogens and inducing immune responses. DCs are very efficient at all forms of endocytosis ...

A recent study reveals that inhibiting certain adhesion receptors on the surface of dendritic cells, the main antigen-presenting cells of the immune system, enhances antitumor responses.

Nature Biotechnology - Dendritic cells, engineered to secrete a T-cell receptor mimic peptide, induce antigen-specific immunosuppression in vivo Skip to main content Thank you for visiting nature.com.

They then stop the antigen capture while upregulating their expression of molecules such as CD86, CD80, and the chemokine receptor CCR7. Dendritic cells will also release cytokines that promote ...

Scientists have discovered why dendritic cell vaccines do not attack ... "We don't know the specific chain of events that Toll-like receptors activate inside dendritic cells to temporarily silence ...

At the same time, the cell-surface receptors that act as co-receptors in T-cell activation are upregulated by dendritic cells. Furthermore, the CCR7 receptor is also upregulated.

Effect of dendritic cells (DC) transduced with chimeric antigen receptor (CAR) on CAR T-cell cytotoxicity. Hyung Chan Suh , Katherine Pohl , Anna Patricia L. Javier , Dennis J. Slamon , John P Chute ...

They carry a receptor on their surface that recognizes small protein fragments – antigens – presented to them by specialized immune cells, including the highly efficient dendritic cells.

Toll-like Receptors & Dendritic Cells in SLE. Toll-like receptors (TLRs) are pathogen recognition systems that identify highly conserved molecular patterns that help distinguish self from non self.

The activated T cells can then proliferate and differentiate. They can become either cytotoxic T cells that release potent cytotoxic chemicals such as perforins and granzyme to kill the invading agent ...

After quinpirole stimulation, the knockout mice had more cell surface D2 receptor. Apparently, FMRP was not involved in the effects of BC1 on the D2 receptor, ... Dendritic BC200 RNA in aging and in ...