Unlike traditional microscopes that use light or lenses, DNA microscopy creates images by calculating interactions among ...
What if you could take a picture of every gene inside a living organism—not with light, but with DNA itself? Scientists at ...
Researchers have developed a new technique — volumetric DNA microscopy — that can create a spatial map of genetic sequences ...
Blum, B., Bakalara, N. & Simpson, L. A model for RNA editing in kinetoplastid mitochondria: RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 60, 189–198 (1990).
the model was trained using plant ribonucleic acid data, also known as RNA. RNA is a large molecule that is present in the majority of living organisms and viruses and has similarities to DNA.
Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...
Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
Once the DNA and RNA are sequenced, a computational model reconstructs their original locations by analyzing the physical links between UMI-tags, creating a spatial map of gene expression.