MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Statement 1: DNA synthesis always proceeds in the 5' to 3' direction.

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune ...

Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. University ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...

Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell’s own machinery to achieve its goals. In a new work appearing online Wednesday in ...

Cryo-EM revealed HIV-1 integrase’s distinct structures as it shifts between its two roles of DNA integration and RNA-binding.

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of ...

Researchers discovered that embryos must clear maternal mRNAs to develop properly. When cleanup fails, it causes aberrant transcription and R-loop formation, which blocks DNA replication, damages the ...

Most of an animal cell’s DNA is stored in its nucleus, packaged into chromosomes that help maintain order. But cancer cells often carry another type of DNA: molecules separate from the rest of the ...