My research focuses on the chiral resolution of cyclopropyl esters, in order to use them to synthesize a chirally-active N-Heterocyclic Carbene (NHC) ligand. NHC-based organometallic catalysts have ...
The introduction of a cyclopropyl group is critical for imparting colibactin with the ability to cleave DNA. Nonribosomal peptide synthetase ClbH and polyketide synthase ClbI are now shown to work in ...
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