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BetMGM NFL Odds: Colts by 6 1/2. Against the spread: Cardinals 2-3, Colts 4-1. Series record: Colts lead 9-8. Last meeting: Colts beat Cardinals 22-16 on Dec. 25, 2021, in Glendale, Arizona. Last week: Cardinals lost to Titans 22-21; Colts beat Raiders 40-6.

Colts defensive coordinator Lou Anarumo will interview soon with the Titans and Giants for their head coaching openings. Anarumo, 59, has been a regular in head coaching interviews for the past couple of seasons. “I’d be lying to you if I said that down the road that wasn’t something that would be a career goal,” Anarumo said earlier this season.

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