Vibrio cholerae presents a unique model of bacterial genome organisation through its bipartite genome, comprising two distinct chromosomes that replicate in a carefully orchestrated manner. The ...

The initiation of chromosome replication is exquisitely regulated in both time and location. It has been estimated that there are 200-400 autosomal replication sequence elements (ARSs) in the yeast ...

Chromosome Dynamics: Although genetic information is encoded in a one-dimensional array of DNA bases, all major DNA processes (replication, transcription and recombination) are controlled by changes ...

Scientists have provided an explanation of how chromosomes undergo structural changes during cell differentiation. The human genome is made up of 46 chromosomes, each of which has a length of about ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...

For biologists everywhere, April 25 is auspicious. It is DNA Day and commemorates the date in 1953 when scientists Francis Crick, Rosalind Franklin, James Watson and Maurice Wilkins published seminal ...

During the replication of the bacterial chromosome, genes close to the replication start point (red) exist in multiple copies, while genes close to the endpoint do not (blue). At faster growth, this ...

In the presence of some disruptive elements, cancer cells are unable to replicate its DNA optimally. While known to be linked to the increase in genetic mutations, the exact mechanism at work remained ...

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about ...