Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...

Chromatin is a structure in the cell nucleus that helps pack DNA tightly by wrapping it around proteins called histones. These DNA-protein units, called nucleosomes, control how genes are turned on or ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

Chromatin remodelers are ATP-dependent motor proteins that dynamically reorganize chromatin architecture, playing essential roles in gene expression, development, and immune function. Dysregulation of ...

Findings surrounding the epigenetic inheritance that takes place in plants may have implications for agriculture, food supplies, and the environment. Now, new research has uncovered a key mechanism in ...

Cancer biology increasingly recognizes that cancer stem cells (CSCs) represent a critical subpopulation within tumors, marked by their self-renewal, ...